By J. C. Czyba, C. Girod (auth.), E. S. E. Hafez (eds.)
During the previous decade vast investigations were performed at the testis. because the observations were released in lots of various journals. it appeared acceptable to compile and summarize many of the pertinent findings in one quantity. Twenty-eight scientists and clinicians from 9 nations have contributed to this ebook. they've got reviewed the literature and awarded their very own, new observations at the developmentaL anatomicaL physiologicaL biochemical and pathological elements of the descended and cryptorchid testis. moreover, a number of participants have evaluated the usefulness of yes animals as versions for systematically learning particular facets of cryptorchidism. it really is was hoping that this quantity will function an invaluable precis and reference for these operating during this sector and that it'll inspire additional study in testicular physiopathology. The editor thank you the participants for his or her enthusiasm, cooperation and meticulous writing of the chapters. The aid of the Departments of GynecologyjObstetrics and the dep. of body structure of Wayne nation collage university of medication. Detroit and the help from the workers of Martinus Nijhoff are gratefully said. The pleased cooperation of pass over Lori Rust and pass over Penny Stoops who helped to variety and gather the amount is so much deeply appreciated.
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By this means they were able to delineate twelve steps of spermiogenesis, which were divided into three phases: I. The Golgi phase. during which the acrosomic granule was formed in the Golgi lone (this consisted of the first three steps): 2. The cap phase (stcps 4-7) dealing with the formation of the head cap over the nucleus: 3. The acrosomic and maturation phase (steps 8-12). Clermont (1963) used the morphological changes of the spermatid nucleus to identify the steps of spermiogenesis, which he subdivided into four main groups, S([-Sd.
During the diakinesis stage, a progressive condensation of bivalents and a terminalization of chiasmata occur. The nuclear membrane disappears at the end of diakinesis and metaphase follows, in which the bivalents are arranged on an equatorial plane. During anaphasc. the chromosomes. each of which consists of two chromatids held together by the unsplit ccntromere. migrate towards opposite poles of the cell. Cell division is often incomplete. and intercellular bridges can be seen between daughter cells.
Nucleolus. These cells are seen infrequently and can easily be confused with young spermatids, which they resemble. After a brief interkinesis, without DNA replication. the secondary spermatocytes undergo the second meiotic division, which yields haploid spermatids. 5 to 1. The germ cells of infertile men, with infertility depending on several factors, have also been studied (Barham and Berlin 1974; Camatini et al. 1978; Castellani et al. 1978; Cotelli et al. 1976). Although many multinucleate cells were found and cellular degeneration was frequent, no significant difference from the norm was found in spermatogonia and spermatocytes.